Livro - Biomarkers in Cancer Chemoprevention

This volume is the product of an attempt to assess our current knowledge and experience with the use of biomarkers in cancer chemoprevention, and is based on an international workshop held at the Deutsches Krebsforschungszentrum (DKFZ), Heidelberg, Germany in February 2000.

It comprises an expert report on the current state of the art on use of biomarkers in cancer chemoprevention, introductory sections reviewing general topics in cancer chemoprevention, and contributions directed to miomarkers exposure, intermediate effect and susceptibility relating to six major cancer sites: skin, colorectum, breast, prostate, liver and upper aerodigestive tract.

Biomarkers that would allow the identification of subjects exposed to carcinogenic agents or of individuals genetically susceptible to cancer would be of great value.

Similarly, markers of intermediate events on the carcinogenic pathway to cancer would facilitate the identification of the stages of carcinogenesis at which such agents might exert their protective effect.